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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD2
All Species:
23.03
Human Site:
T308
Identified Species:
33.78
UniProt:
Q9NNW7
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NNW7
NP_006431.2
524
56507
T308
T
G
K
E
D
T
G
T
F
D
T
V
L
W
A
Chimpanzee
Pan troglodytes
XP_001166615
481
51948
C278
G
T
R
F
L
R
G
C
A
P
S
R
V
R
R
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
T308
T
G
K
E
D
T
G
T
F
D
T
V
L
W
A
Dog
Lupus familis
XP_850181
509
55065
T295
S
G
K
E
D
V
G
T
F
D
T
V
L
W
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLT4
524
56434
T308
S
G
K
E
D
T
G
T
F
D
T
V
L
W
A
Rat
Rattus norvegicus
Q9Z0J5
526
56406
T310
S
G
K
E
D
V
G
T
F
D
T
V
L
W
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001116163
518
56137
S302
L
G
T
E
E
T
D
S
F
D
T
V
M
W
A
Frog
Xenopus laevis
NP_001080052
504
54666
I288
S
G
K
E
G
V
D
I
Y
D
T
V
M
W
A
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
F383
S
T
E
S
E
E
V
F
E
G
E
Y
N
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
V382
T
G
E
E
A
E
D
V
Y
D
T
V
L
W
A
Honey Bee
Apis mellifera
NP_001171496
537
59227
F323
R
Q
T
H
Q
D
T
F
D
T
V
L
F
A
I
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
T441
W
P
K
K
N
E
E
T
G
E
M
Q
E
V
S
Sea Urchin
Strong. purpuratus
XP_797733
490
53044
F279
G
Q
E
G
H
G
E
F
D
T
V
M
F
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48641
499
53852
E286
V
I
S
S
H
G
E
E
F
V
A
D
V
V
L
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
V268
I
V
K
V
E
K
N
V
E
T
D
K
L
K
I
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
D267
E
G
E
Q
S
I
S
D
V
D
H
L
I
W
A
Conservation
Percent
Protein Identity:
100
91
98.2
83.2
N.A.
84.5
82.6
N.A.
N.A.
72.9
68.6
47
N.A.
48.9
53
40.7
55.7
Protein Similarity:
100
91.2
99
91.4
N.A.
91.5
90.8
N.A.
N.A.
86
82.2
62.2
N.A.
62.4
68.5
56.2
69.8
P-Site Identity:
100
6.6
100
86.6
N.A.
93.3
86.6
N.A.
N.A.
60
53.3
0
N.A.
60
0
13.3
0
P-Site Similarity:
100
26.6
100
93.3
N.A.
100
93.3
N.A.
N.A.
80
73.3
20
N.A.
73.3
6.6
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
32.8
34.7
Protein Similarity:
N.A.
N.A.
N.A.
51.7
53
52.4
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
7
0
7
0
0
13
57
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
32
7
19
7
13
57
7
7
0
0
0
% D
% Glu:
7
0
25
50
19
19
19
7
13
7
7
0
7
0
0
% E
% Phe:
0
0
0
7
0
0
0
19
44
0
0
0
13
0
0
% F
% Gly:
13
57
0
7
7
13
38
0
7
7
0
0
0
0
0
% G
% His:
0
0
0
7
13
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
7
7
0
0
0
7
0
7
0
0
0
0
7
0
13
% I
% Lys:
0
0
50
7
0
7
0
0
0
0
0
7
0
7
0
% K
% Leu:
7
0
0
0
7
0
0
0
0
0
0
13
44
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
7
13
0
0
% M
% Asn:
0
0
0
0
7
0
7
0
0
0
0
0
7
0
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
0
13
0
7
7
0
0
0
0
0
0
7
0
0
0
% Q
% Arg:
7
0
7
0
0
7
0
0
0
0
0
7
0
7
7
% R
% Ser:
32
0
7
13
7
0
7
7
0
0
7
0
0
0
7
% S
% Thr:
19
13
13
0
0
25
7
38
0
19
50
0
0
7
0
% T
% Val:
7
7
0
7
0
19
7
13
7
7
13
50
13
13
13
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
57
0
% W
% Tyr:
0
0
0
0
0
0
0
0
13
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _